Your English writing platform
Discover LudwigSuggestions(2)
Exact(8)
Since annotation with a term implies annotation with all its predecessors, ancestral terms are redundant.
When diseases mapped to multiple ancestral terms, we chose the ancestral terms occurring most frequently across all diseases to represent each disease, as this reduced the number of classes represented in the network, making the disease clusters easier to identify.
Traditionally, if a domain is associated with a GO term, it is also associated with all ancestral terms of the GO term with equal relevance.
Still another informatician may want to include all ancestral terms for each term found in the text (i.e. terms not present in the original text).
Genes and proteins are often annotated with terms from different levels of the GO hierarchy, which can lead to functional profiles that contain ancestral terms.
We define anc as a function that, for a given term or set of terms, returns the set of ancestral terms (i.e. inferred super-classes).
Similar(52)
The ancestral term found by traversing up the GO hierarchy.
The former F1 cluster lies closer to the F2 cluster due to a common ancestral term "binding".
Based on these analyses, we proposed a novel strategy, namely RSC, to measure the relevance between domain and ancestral term based on semantic coverage.
To get a broader overview of the GO terms assigned to genes, the terms were traced back to the ancestral term at different levels in each of the gene ontology classes biological process, molecular function and cellular component.
Generally, for a given function, the ancestral term is more likely to describe the given function than its descendants because the semantics of its ancestors is more general and has more power to describe function.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com