Sentence examples for ancestral regulation from inspiring English sources

While Lagomarsino et al. (2007) found significant similarity in auto-regulation within TF families [ 17], this has recently been suggested to largely result from convergent evolution rather than conservation of ancestral regulation [ 28].

On the other hand, the recG gene of some α-Proteobacteria appears to be regulated by LexA, suggesting that the presence of LexA-binding sites upstream of recG reported in the Vibrionaceae might be due to an ancestral regulation of this gene.

We reasoned that, if an ancestral regulation of Dlx expression had dissociated and evolved independently in the different odontodes after its cooption at different locations, there should be more differences between expression patterns when comparing structures in one organism (serial homology) than when comparing homologous structures between extant gnathostomes (specific homology).

It should also tell us what are the ancestral regulations that were robust enough to be maintained in cnidarians and vertebrates.

Two hypotheses could explain this observation: either most E. coli regulation mechanisms were established after the lineage divergence, or some E. coli specific regulations are ancestral in origin, but they did not correspond to the demand for B. aphidicola regulation, and so the operon map dynamics of this latter species was not influenced by specific ancestral regulations.

Our results suggest that the assembly of the B. aphidicola genes in TUs had not been constrained by their ancestral specific regulation (as far as this can be accessed from the specific regulation of their orthologues in E. coli).

In this context, we propose the hypothesis of an vertebrate ancestral morphogenesis regulation system with independency between the pro-proliferation and anti-proliferation signals (as in thelodonts and sharks) explaining the ability to grow single-axis and bent-axis structures, and a later evolutionary event leading to the enamel knot system in the lineage leading to extant mammals (Fig.  9).

This pattern led us to hypothesize that the evolution of caste diphenism in honey bees involved adoption of TOR signaling as an ancestral mechanism for regulation of phenotypic plasticity in response to variation in nutrient status.

Our work in yeast further indicates that this may be an ancestral mode of regulation, and provides insights into the molecular mechanism by which it is achieved.

Hence, the ancestral dsx splicing regulation observed in Apis (and in lepidopteran) seems to have been stably maintained in Aedes aegypti, which constitutes the first dipteran species reported with this type of splicing regulation.

Among the 16 polycistronic similar TUs, 6 have lost the first gene of the TU (and so their ancestral promoter and regulation), 3 have lost their final gene(s), and 5 their internal gene(s).