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Thus they emerge as good candidates for a group of truly conserved ancestral master polarity regulators.
The probability of two identical substitutions occurring independently in different repeat copies is low; thus, groups of two or more substitutions shared by two or more repeat copies likely reflect substitutions that occurred along the ancestral master element lineage.
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Today, the spirits of the Vazimba are revered as tompontany (ancestral masters of the land) by many traditional Malagasy communities.
In addition, as alignment accuracy decreases with sequence divergence (Lunter et al. 2008), we limited our analyses to element copies ≥80% identical to their respective master gene (ancestral) sequences, with a minimum overlap of 300 bp.
That damage began after the Spanish conquest, with forced labor in mines far from ancestral homelands and the colonial masters' use of people as currency in business deals.
These files contain pairwise alignments of a single non-LTR element sequence and its inferred master gene (i.e., ancestral) sequence; we identified the subset of each genome masked by non-LTR element master sequences.
First, for each species, we used RepeatScout to estimate a consensus sequence from all genomic copies of each Gypsy/Ty3 family/subfamily; this consensus represents the master gene (i.e., ancestral) repeat sequence for the family/subfamily.
For each repeat element family, we first used RepeatScout [ 41] to estimate a consensus sequence from all genomic repeat copies; this consensus represents the repeat family's master gene (i.e. ancestral) sequence.
Hence the absence of the derived allele in the highlander populations can be seen as a twofold consequence of selection: against the damaging excessive activity of a hypoxia master regulator gene, favouring instead the ancestral variant capable of conferring better endurance and VO2max plasticity in a mildly hypoxic environment.
My lord and lady, whose ancestral titles.
Although Shannon worked largely with analog technology, he also has some claim as the father of the digital age, whose ancestral ideas date back not only to his 1948 paper but also to his master's thesis, published a decade earlier.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com