Sentence examples for ancestral maps from inspiring English sources

Ancestral maps allow the effect of recombination rate to be tracked on evolutionary time scales.

The human-chimpanzee map is the only one completed so far, but we can formulate expectations for the properties of the additional ancestral maps.

We believe that inclusion of multiple ancestral maps in comparative analysis of extant species will help advance our understanding of the evolution of recombination rate and its control.

The impact of population size on the evolutionary rate of recombination patterns will become clear as more recombination maps of extant species become available for comparison to corresponding ancestral maps.

This suggests that the ancestral map possess a resolution comparable to the maps of extant species, despite the different observational base.

The ancestral map therefore describes the average recombination rate on a time scale much longer than recombination maps based on patterns of polymorphism in extant species.

In addition, whereas polymorphism based maps can measure the effect of more than one crossover between sites, the ancestral map is only able to detect single crossovers that identify the transition between genealogies in the model.

We propose a solution in the form of a variant of the consecutive ones problem, which was also used in physical mapping of chromosomes and adapted to ancestral mapping (Chauve et al., 2010a; Chauve and Tannier, 2008; Ma et al., 2006; Ouangraoua et al., 2009; Tannier, 2009).

For this reason, further fine mapping of the region is needed and the region may also benefit from trans-ancestral mapping [ 96].

Confirmation of the causal gene will require a combination of re-sequencing, trans-ancestral mapping, and correlation of genetic association data with expression data.

This approach can be complemented by trans-ancestral mapping with the most likely common causal variant (that is, the effect identified by Köttgen and colleagues) predicted to be most strongly associated with urate levels (and gout) between diverse ancestral groups.