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We also need to adopt a proxy ancestral activity regime: bending, stretching, carrying and manual labour.
Among specifier proteins, NSPs represent the ancestral activity.
FLCE maintained the ancestral activity with high substrate specificity and was unable to digest medaka egg envelope.
The clade II enzyme gained two specific cleavage sites, N-ZPd and mid-ZPd but lost the ancestral activity.
Accordingly, it has been proposed that this polymerase activity is likely to have been the ancestral activity of the Thg1 enzymes across the superkingdoms of life [ 6].
Because OoTPS1 from O. officinalis was an EGS, one scenario could be that the ancestral activity of the other six OryzaTPS1s is EGS.
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In most families, these ancestral activities are performed independently by the hostess.
One million people, for example, visit Scotland each year, motivated by their ancestral activities and generating £730 million for the economy, according to tourism authority VisitScotland.
Although the phylogenetic and functional analyses point towards the maintenance of ancestral activities, the expression profiles indicate functional partitioning in the salmon elovl5 paralogs.
In the 'molecular exploitation' model of a biochemical pathway, the terminal products of a synthetic pathway mediate the more ancestral activities.
For example, duplication could permit each copy of a multifunctional protein to specialize on a subset of the ancestral activities, thereby reducing pleiotropy [ 23, 24].
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