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But sometimes we look down and notice bite marks on ourselves, as when we found that the Internet enables a culture of inhumanity, universal surveillance, or anarchic proliferation.
Anarchic proliferation reduces interstitial space and leads progressively to compression of small vessels, resulting in ischemic changes in the tissue.
While cancers are associated with alterations of cellular cycle inducing anarchic proliferation, neurodegenerative diseases are on the contrary associated with a cellular deregulation leading to neuronal death.
RB, similarly to a puppet master, coordinates multiple cellular functions in a large variety of contexts, and its inactivation therefore goes beyond the simple inactivation of a red light on the road to anarchic proliferation.
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Yet if this side of postmodernism — it could be called the tragic or tragicomic side — is gravely shadowed by silence, the comic-manic side sometimes seems to be in rapid flight from it: think of the anarchic proliferations of Thomas Pynchon, the metafictional garrulity of William Gass, the perpetual movement of Auster.
Defects in the UPS can lead to anarchic cell proliferation and to tumor development.
Anarchic cell proliferation, observed in some leukemia and in breast and ovarian cancers, has been related to dysfunctioning of cytoplasmic or receptor tyrosine kinase activities coupled to p21 Ras.
The best known effectors of Ras are the Raf kinases which stimulate cell cycle entry via ERK/MAPkinase activation, leading to anarchic cell proliferation in cancers.
Also, a tumour could decrease Brownian motions, because of anarchic cell proliferation and hypercellularity.
Many diseases are associated with cellular dysfunction, such as aggregation of insoluble compounds, uncontrolled cell death, and anarchic cell proliferation as in cancers.
The proliferation of websites to encourage, facilitate and shelter leakers is so anarchic that two aspiring anti-corporate leak sites are both claiming rights to the rubric "GreenLeaks" and muttering about legal consequences if the other side doesn't back down.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com