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The protein interaction with corresponding genes was analyzed using the String 9.1 website (http://string-db.org/).
Protein protein interactions of pJAB1 were analyzed using the STRING (version 9.1) software.
Gene interaction networks were analyzed using the STRING (http://string-db.org/) database of known and predicted protein interactions, which included direct (physical) and indirect (functional) associations.
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To search for reported physical and/or functional associations between the enriched protein coding genes, the data was analyzed using the Search Tool for the Retrieval of Interacting Genes/Proteins (STRING) database [ 11].
Differences among the results of the string test (mm) and phagocytosis (gate %) were analyzed using the Mann-Whitney U-test.
A protein interaction network of the differentially regulated proteins was analyzed using the online database resource Search Tool for the Retrieval of Interacting Genes (STRING 9.1, http://string-db.org/) [ 53].
Data were analyzed using the χ2 test.
Forty five binding partners (Table S4) of the wild type eIF5B were identified in two independent biological replicates and the interactome was analyzed using STRING software (http://string.embl.de) (Fig. S6).
In the central part of Fig. 5, the protein interaction of the above-mentioned 28 down-regulated genes was further analyzed using String 9.1.
Functional protein association networks of genes identified from the genomewide RNAi screen (Lee et al., 2010) were analyzed using STRING (http://string-db.org/) (Franceschini et al., 2013).
In addition, overlapping target genes in all three tissues were analyzed using STRING (http://string.embl.de).de
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