The gene categories that were enriched in the DEGs were analyzed to address the question of whether the genomic and heat shock perturbations had affected any specific gene categories (details in Additional file 3: Table S2 and Additional file 4: Table S3).
In a "case-control" association study, the genotype frequencies of some polymorphisms located in a particular gene are analyzed in order to address whether there is or is not an increased frequency of a single allele or genotype in patients, compared with controls.
Experiments involving two variables were analyzed using two-way ANOVA to address whether they interact with each other in a synergistic manner.
We then analyzed BrdU incorporation in the GFP+ cell population to address whether the increase in the number of pericytes is due to cell proliferation.
To address whether Zn II -curc affected mutp53 stability we analyZn II -curcluent proliferaffectedBR3 cells (carrying R175H p53 gene mutp53on) compared with HCT116 cellstabilityg wep53.
To address whether this could be the case, we analyzed the ability of both these lines to respond to BMP4 after a 3 day culture in N2B27, when the elimination of defective cells occurs.
a) To address whether TERT rescues nuclear morphology defects, we analyzed two different HGPS-patient derived fibroblasts before and after transduction with hTERT, and cultured these cells for an extended period of time.
To address whether sacy-1 plays essential roles during oogenesis, we analyzed the sacy-1 (tm5503 ) deletion allele generated by S. Mitani.
To address whether Pasiflora1 and Pasiflora2 localization is similarly affected, we analyzed their distribution in the hindgut of stage 15 embryos homozygous for amorphic mutations in SJ proteins.
We analyzed the expression of Tra1-F3744A in wild-type and SUP3-containing strain backgrounds to address whether the suppressor altered the expression of Tra1.
