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Our finding that elevated expression of PTK6 transcript correlates with adverse outcomes for patients with breast cancer in all cohorts analyzed is consistent with a recently reported correlation between PTK6 mRNA levels and tumor grade based on analyses of 44 tumors [31].
Similarly, the strong and specific staining for miR-143 and miR-145 in the iris sphincter at all developmental stages analyzed is consistent with recent reports that demonstrate the key role of these two miRNAs in modulating smooth muscle cell proliferation and differentiation [ 46].
The higher expression of mFwe transcripts in tissues such as eyes and brain (supplementary material Fig. S1A D), as compared with their abundance in the rest of the tissues analyzed, is consistent with the described expression and function of dFwe in the Drosophila nervous system (Yao et al., 2009).
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Overall, the patterns of change across the biomarkers analyzed are consistent between the two groups.
As a proof of concept, the wild-type and two engineered strains analyzed were consistent with published experimental results.
Moreover, the expression patterns at 48 h of the genes analyzed was consistent with direct or indirect regulation of those genes by ex-siRNAs of different classes.
In addition to being more or less variable, the magnitude of the rate of variability of the gene families analyzed was consistent across all five genome capture samples and the IQ07 positive control.
The apparent absence of O-mG adduct formation in vitro by microsomes from any of the mouse tissues analyzed was consistent with the fact that N-mG was much more abundant than O-mG in vivo, in AOM-treated mice (Table 1), which has been noted previously with adducts formed by another compound.
Home-cage circadian rhythmicity measured by assessing heart rate, core body temperature and locomotor activity in wt mice analyzed in this study were consistent with previously reported data (Gaburro et al., 2011; Sanchez-Alavez et al., 2011).
In control embryo (Fig. 5A), the fbasic (red colour) in each second analyzed was kept consistent along the examination period.
In general, the majority of gene sequences previously analyzed in hominids supports a chimpanzee-human clade, although a smaller proportion of the analyzed genes is consistent with a chimpanzee-gorilla or human-gorilla clade [36] [40].
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