Data were analyzed for a randomized complete block design with repeated measures.
These unspliced single exon gene models are filtered out early on in the pipeline and have not been analyzed further (for a complete list with genomic co-ordinates see Additional file 3: Page – Single exon gene models).
The samples were collected using lavender top tubes containing K2EDTA and analyzed for the complete blood count (CBC) parameters within 24 hours of collection with a laboratory reference system (SYSMEX SF-3000 hematology analyzer).
The full-length RRM-containing human gene products were also analyzed for their complete domain architectures using HMMScan [ 30] against HMM profiles of Pfam families.
Patients were analyzed for achieving complete cytogenetic remission (CCR), major molecular remission (MMR), and molecular remission ≤0.01 % on the international scale (MR), if at least one sample of sufficient quality was available.
Whereas maternal serum and milk were analyzed for the complete set of 87 environmental chemicals, the 20 PCDDs, PCDFs, and coplanar PCBs were not determined in cord blood, cord tissue, and placenta due to insufficient sample sizes combined with low lipid contents.
Aliquots of EDTA-collected blood were analyzed for complete blood counts by a Beckman-Coulter AcT blood analyzer (Beckman-Coulter Inc., Fullerton, CA, USA).
To determine absolute cell counts, a small volume of blood was analyzed for complete blood count (CBC) with differential mode.
Whole blood was immediately analyzed for complete blood count, i.e., red blood cell (RBC), haemoglobin (HGB), hematocrit (HCT), white blood cell (WBC) and platelets (PLT), using the fully automated ABX Pentra 60C+ Analyzer (Horiba ABX, Montpellier, France).
