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The measurements were performed at atmospheric pressure, and the studied temperature range covers the liquid phase of the analyzed compounds.
The elemental analysis, mass spectroscopy, NMR and infrared spectroscopy have been used for basic characterization of analyzed compounds.
Most of them require relatively high amounts of the analyzed compounds, or the use of labeled target molecules.
The regression analysis of the data indicated that the steric effect of N-substituted group on tropane of analyzed compounds critically affected the agonistic activity to muscarinic receptors.
Limits of detection (LODs) in the sub-picogram per litre level from 0.030 to 0.330 were achieved for all analyzed compounds.
Data provide important information that can be useful to a deeper understanding of the mechanism of actions of the analyzed compounds.
Among the analyzed compounds with the lowest free binding energy to the arginine kinase active site (<−6.96 kcal/mol), resveratrol was chosen for subsequent assays.
Molecular docking studies of the synthesized library of hybrid structures against glucosidase enzyme were performed to describe ligand-protein interactions at molecular level that provided an insight into the biological properties of the analyzed compounds.
These analyses have shown the ubiquitous presence of chloro-substituted organophosphorus flame retardants and bisphenol A, while other analyzed compounds were occasionally found at concentration between the limit of detection and quantification.
Under the optimized conditions for all analyzed compounds, the linearity was from 2.5 to 400 μg L−1, and limit of detections (LODs) were between 0.02 and 0.08 μg L−1.
The plan was to make the mass to concentration tie-in for the selected analyzed compounds (Benzene, Toluene, and Total Petroleum Hydrocarbons) from the PSG in mass (nanograms) with both the soil and water samples in concentration.
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