We analyzed branching morphogenesis in neonatal tissues using a computer-based method that allows examination of temporal and spatial alterations in branching morphogenesis as a result of experimental manipulations.
In this case, the analyzed branches are of approximately equal lengths, that is, form a balanced tree (table 1 and fig. 3 A ), a situation in which the RGC analyses are most reliable (Rogozin et al. 2008).
Specific GO categories (for biological processes) were found to be statistically overrepresented in 6 of the 34 analyzed branches (fig. 6), with transposition/DNA recombination and fatty acid biosynthesis being the most frequent GO term (found in two lineages each).
The short pipeline (four stages) results in short conditional branch delays; a difficult to analyze branch prediction logic or a branch target buffer can be avoided.
Next we used Reversed Strahler analysis [45] to analyze branching pattern and complexity of the ddaC neurons.
However, two parallel changes (Y->X in the branch leading to the outgroup species and in the analyzed internal branch) also could explain the pattern in Figure 6, and this effect might be especially important when the number of outgroup species is small.
To check whether SFR is a general property of signal transduction at pathway junctions, we next analyzed another branch point of the TRAM-dependent component of the TLR4 pathway: TRIF to TBK1, TRAF6 and RIP1 (Figure 1A).
To investigate evidence for positive selection in the 11S globulin genes, we analyzed five branches, i.e. branches A- E, which represent the major origin events in the evolution of the 11S globulin gene families, e.g. branch B represents the origin of G. max 11S globulin gene family.
