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Although the EQS-H is convenient to use from the point of view of both hospitals and patients, its psychometric properties are compromised by a high rate of 'did not apply to me' responses (NA), analyzed as missing data, and by a skewed score distribution.
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The data were analyzed as observed, without imputation for missing responses.
Weight change, the primary study outcome, was analyzed as intention to treat, with baseline substitution for missing data.
Abundance information was analyzed as previously reported12.
The data were analyzed as previously described44.
DNA damage pathway was analyzed as follows.
Supernatants after immunoprecipitation were analyzed as controls.
and analyzed as previously described [10].
Luciferase expression was analyzed as above.
Data were analyzed as described above.
All phenotypes were analyzed as quantitative trait.
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