Requisite leachables testing of pharmaceutical products is commonly conducted with pre-defined analytical methods on a subset of materials intended to be representative of the marketed product.
Sample analytical parameters for a subset of spoil and coal refuse samples from TN that is used as examples in this paper are provided in Table 1.
To evaluate analytical sensitivity, a small subset of sera from the field collection (n = 3) and all the sera from the experimentally infected animals were also serially diluted (twofold) in negative serum, and tested with the procedure described above.
We applied the same analytical procedures to this subset as to the entire dataset — i.e., we performed a PCA, assessed the number of significant eigenvectors (8 instead of 9 for the subset), performed t-tests on scores, counted the directionality of individual tests (Additional file 4: Table S2) and then calculated the proportion of variation attributable to each direction of adaptation.
Analytical trials on different subsets of nonmolluscan outgroups altered outgroup topology and support values of some basal ingroup nodes but did not change the ingroup topology.
To address issues of analytical rigour and trustworthiness, a subset of transcripts were double-coded by KB.
To address issues of analytical rigor and trustworthiness a subset of transcripts were double-coded by JK.
The 3.6-min helical SPECTs were reconstructed with OSEM (70 iterations × 8 subsets) including the analytical scatter model.
Previous analytic methods generally have analytical selectivities of 102 103, with the exception of BEAMing and MutEx/ACB-PCR for a limited subset of restriction sites [3], [4].
We used a commercially available analytical procedure for quantification of DC subsets in whole blood PBMC.
COPA is a method to search for marked overexpression of particular genes that occur only in a subset of cases, whereas traditional analytical methods based on standard statistical measures fail to find genes with this type of expression profile [19].
