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Further problem definition can determine the appropriate analytical plan for risk characterization.
The analytical plan for more fully characterizing risk in this instance would focus on measurements of the ecological value (the functional role of these enzymes in the soil ecosystem).
Each study adopted collaboration guidelines and established a consensus on phenotype harmonization, covariate selection and an analytical plan for within-study genetic association and prospective meta-analysis of results across studies.
Problem formulation has been widely considered from the perspective of transgenic plant risk assessments [ 20, 29, 30, 34] as a means to identify the nature of questions that are germane to a given case of risk assessment and to arrive at a practicable analytical plan for risk characterization.
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See Statistical and analytical plans for the rationale for planned sample size.
Results will inform the analytical plan of data provided by other regions in Spain.
As this may have an impact on the immune responses following immunization [ 16, 17], effort was made to document this, and the analytical plan provided for a comparison between those who received and those who did not receive antipyretics.
Investigators who would like access to the trial data set are encouraged to submit a brief application, outlining rationale and analytical plan, to the trial management group for approval for additional studies.
We performed an extensive, systematic pathologic review by expert breast pathologists using contemporary classifications to confirm the diagnosis of pure DCIS and a rigorous, predefined statistical analytical plan, including pre-specified cut-points for the DCIS Score and study objectives.
Data management and analyses were conducted according to a pre-specified (common for all participating countries) statistical analytical plan that provided descriptive summary statistics only [mean and standard deviation (SD) for continuous data; number and percentages for categorical data].
The key was obtained in exchange for the locked dataset and detailed analytical plan.
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