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The optimization of analytical parameter was performed by response surface method using Box Behnker and central composite designs.
The normalised signal used as analytical parameter is obtained from measurements in transflectance mode and the results are compared with those obtained by transmission mode.
In a bid to examine the influence of variation of each analytical parameter on the model, sensitivity analysis has been performed.
The variance varied with the analytical parameter but for most parameters the uncertainty was satisfactorily low (of the order of 3 10% expressed as the relative standard deviation, which is considered to be satisfactory for waste characterization).
It is evident that in both methods, there is an excellent correlation between the analytical parameter and the concentration of the drug.
We evaluated effects of experimental data characteristics and key analytical parameter settings on imbalance detection.
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LC MS/MS provides a multitude of analytical parameters that may be adjusted to enhance the analytical selectivity of an analyte.
DFe concentrations were measured by flow injection with online preconcentration and chemiluminescence detection using the exact protocol, instrument, and analytical parameters as described previously50.
Sourvinou, I. S., Markou, A. & Lianidou, E. S. Quantification of circulating miRNAs in plasma: effect of preanalytical and analytical parameters on their isolation and stability.
The analytical parameters (sensitivity, selectivity and reproducibility) were evaluated.
For the optimization of analytical parameters Doehlert design was used.
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