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Finally, an additional analysis with the exclusion of subjects <40 years of age (to focus more exclusively on type 2 DM) was performed.
Interestingly, if the invertebrate STIMs were clustered as an independent group in the divergence analysis (with the exclusion of the C-terminal divergent domain sequences), there was no significant difference between STIM-1 and the invertebrate cluster (θ = 0.001).
We did a sensitivity analysis with the exclusion of these trials and no addition of one trial and participant.
To further avoid unaccounted variations due to sicker patients being transferred out on weekends, we repeated our analysis with the exclusion of these patients.
Cluster analysis showed that 21 of the above 23 four diagnostic methods' information had automatically entered the cluster analysis, with the exclusion of "chest pain" and "less moss".
These patients were therefore included in our analysis, separate analysis with the exclusion of these 10 patients did not lead to any major changes in results.
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The meta-analysis with the exclusion of the EPIC study showed a 0.18-SD (95% CI: 0.10-, 0.25-SD; P = 3.34 × 10−6) increase in l-ascorbic acid per effect allele (Table 3, Supplemental Figure S2).
Our figures could have underestimated the number of workers 'ever exposed' in the REP because workers with <1 year of employment were not included in the analysis consistent with the exclusion of short term workers in many occupational epidemiological studies.
Table 2 shows the distribution of the number of admissions by age, sex, and deaths for the analysis dataset, with the exclusion of admissions detailed in the specification (see table 1) and maternity admissions.
However, in the joint analysis with the other exclusion criteria, the associations were no longer significant.
A sensitivity analysis was performed with the exclusion of children who had CKD stage V or renal transplants.
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