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In the third setting, Kansas City, Missouri, a cohort design with matched control analysis will be implemented.
A linear mixed model analysis will be implemented for each factor (sleep quality and depression) at each time point.
Moreover, we intend to perform other simulation analysis in the context of cell cycle modelling using XPPAUT: first of all the bifurcation analysis will be implemented and will be also available through the web interface.
The primary analysis will be implemented using a multivariable generalised linear model to investigate between-group differences in mean WOMAC pain score at 12 months follow-up, adjusting for minimisation variables and baseline value of the primary outcome.
This analysis will be implemented using a linear regression model of the final measure on each scale including as covariates the value of the initial measure, gender, initial SF (300 599 μg/L or 600 1000 μg/L as a binary variable) and site (Melbourne or Brisbane as a two category variable).
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27 A meta-analysis will be implemented with the Cochrane Collaboration Review Manager (RevMan V.5.2.3) software.
Failure Mode and Effect Analysis method will be implemented in this study in order to achieve the aim of this study.
Once texture analysis tool will be implemented in the workstation used for clinical purpose, texture features extraction will be faster as it is currently for conventional parameters.
Especially, the execution of actions dependent on the analysis result will be implemented as an extra agent, thus can be used independently of the underlying event detection (e.g. file system change, infrastructure change, etc).
Between-trial variation in age-range, other eligibility criteria, and treatment protocol, a common analysis plan will be implemented separately within each participating trial.
The same analysis approach will be implemented to explore the stability of diagnosis confidence between time of first confirmed diagnosis and 6-month follow-up.
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