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The relative integrals from plasma analysis were analysed using a one-way analysis of covariance.
Data from QRT-PCR-based gene transcription analysis were analysed using SPSS version 16.0 statistical package.
Variables that were considered significant in the univariate analysis were analysed using multivariate analysis.
Biological pathway and network analysis were analysed using an Ingenuity Pathway Analysis software (IPA).
All variables in the multivariate analysis were analysed using the forced entry procedure.
The categorical data of the segmental analysis were analysed using the chi-square test or Fisher's exact test.
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Data for the meta-analysis was analysed using Review Manager (RevMan, Version 5.2., Nordic Cochrane Centre, http://ims.cochrane.org/revman).org/revman
Statistical analysis Data were analysed, using SAS version 9.1.
Analysis reports were analysed using a standardised procedure that followed the steps of the ORION method.
Radioligand binding and Scatchard analysis data were analysed using GraphPad Prisim V4.0 programme (GraphPad Software Inc., San Diego CA, USA).
Statistical analysis Data were analysed using SPSS for Windows (version 11.5) and are presented as proportions or means±SD.
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