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The microbiologist performing the analysis was masked to the diagnosis.
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The data analyst was masked to the cluster allocation until analysis was complete.
The case-control status of the samples was masked to the person involved in chemical analysis.
Image analysis was performed by three neuroradiologists who were masked to the diagnosis and who were able to access coronal images of the LGN only, without optic nerves and optic chiasm.
Investigators (R.F. and A.F). were masked to treatment groups until analysis was complete.
Once identified, the repetitive element regions were masked to avoid bias in further analysis.
Finally, images were masked to exclude non-GM voxels from the analysis.
Investigators were masked to treatment.
Since we were interested in identifying differences between relief and reward activity in the regions identified as showing a main effect of either relief or reward, the results from the relief>reward analysis were masked by the thresholded statistical map showing significant positive relief activation.
In the original analysis, this response was masked owing to the preponderance of Caucasian patients in the study.
Thus, about one-third of the tandem repeats identified in the masked genome were components of genes, as the repetitive fraction was masked out prior to analysis.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com