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To estimate errors of GFRFDG and ERPFFDG, the reproducibility of the VOI choice for FDG TAC analysis was assessed with data from subject group 1 (Table 1), having high differences between their reference values, age, and gender.
Nodal support within the phylogenetic trees within the parsimony analysis was assessed with bootstrap percentage after 1000 re-sampling steps [45] and within the maximum likelihood analysis with jackknife percentage after 1000 re-sampling steps with 30% character deletion [46].
The trend analysis was assessed with Cochran-Armitage trend test.
Statistical analysis was assessed with the Analyst Interface of the SAS Statistical Analysis Systemm) Version 9.2.
Statistical significance for global analysis was assessed with a false discovery rate (FDR) of 1%, q-value ≤0.01.
The adequacy of the factor analysis was assessed with the Kaiser-Meyer-Olkin measure and the Bartlett's test of sphericity [ 15].
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All the main constructs included in the analysis were assessed with self-report measures based on multi-item scales.
Stationarity and convergence of the Bayesian analysis were assessed with Tracer v1.5 [ 102].
Interobserver reproducibility analysis was assessed in 20 patients with repeated measurements by two experienced physicians using the intraclass correlation coefficient (ICC).
An ad hoc risk analysis was assessed according to international guidelines [ 28], with particular focus on the Investigational Medicinal Products (IMP) [ 29].
Lungs were excised and weighed with a balance (balancepost-exsang).. Agreement between lung weights measured with the balance (considered as reference) and those estimated by quantitative analysis of CT was assessed with Bland-Altman plots.
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