Our analysis uncovers major differences in the regulation of c-myb transcription in the HoxA9/Meis1-transformed cell line compared with the HPC model, which could explain the overexpression of c-myb observed in leukemic cells.
Some recent studies have used this type of multivariable risk-stratified analysis and have uncovered major variations in net relative treatment benefit that were not identifiable by examining patient factors one at a time.
The expression analysis uncovered remarkable differences between male and female gonads, while male and female brains were almost identical.
Statistical analysis uncovered significant intergroup differences in ER mRNA expression.
This analysis uncovered 3 major network domains and some smaller modules that were grouped according to their relative fold change (T2 vs. T1) that corresponded to distinct ontologies.
This is something that I hadn't given much thought to, but that I thought was worthy of analysis because it would reveal major differences.
Analysis uncovered both sex and genotype, brain region-specific differences in protein expression.
Besides identifying TP53, PTEN, HRAS and MET as major altered HNSCC hallmark genes, this analysis uncovered 34 novel candidate genes altered.
Differential transcript abundance analysis uncovered the dynamic transcript abundance patterns of flowering correlated genes and their major functions based on Gene Ontology (GO) analysis.
Analysis confirmed major differences between EphB1- and IL-6-mediated gene expression profiles regulating astrocyte reactivity/proinflammatory cascades and homeostatic pathways (Fig. 3e, f; Supplementary Fig. 4).
The analysis uncovered evidence supporting the hypothesized link.
