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In addition, we restricted analysis to trials where a correct answer was given (5349 out of 5424 observations).
We limited analysis to trials in which the distractor was present in the display and response in the immediately preceding trial had been correct.
Our approach was to limit the analysis to trials of higher quality.
We restricted the analysis to trials reporting means and standard deviations, excluding means that were estimated from medians.
When we restricted the analysis to trials of ≥24 weeks, the HbA1c in 10 trials was 1.19% lower (0.98 1.41; I = 71.2%) in the metformin groups versus placebo.
16 We planned a sensitivity analysis to assess for the robustness and consistency of the primary analysis by restricting analysis to trials with a low risk of bias.
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Adaptive trial designs use interim data analysis to amend trials, and have been recognized for more than a decade as a way to increase trial efficiency, partly by the increased probability of demonstrating a drug effect if one exists.
Finally, we limited our analysis to randomized trials only.
Where model fit was indicative of inconsistency, we firstly planned to restrict analysis to those trials with adequate allocation concealment.
After acquisition, all data epochs with values exceeding ± 2500 fT were rejected from further analysis to exclude trials with eye-blinks and movement artifacts.
Following data acquisition, all epochs with values exceeding +/− 2500 fT were rejected from further analysis to exclude trials with eyeblinks and movement artifacts.
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CEO of Professional Science Editing for Scientists @ prosciediting.com