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To our knowledge, JNuke is the first tool that has achieved this integration, which enables static and dynamic analysis to interact in novel ways.
The Snf5 subunit is shown by crosslinking-mass spectrometry (CX-MS) and subunit deletion analysis to interact with the ATPase domain of Snf2 and to form a submodule consisting of Snf5, Swp82, and Taf14.
The research team used a similar approach that incorporated a multi-phased requirement elicitation and case analysis to interact with engineers and document their visualization requirements during risk assessment process.
For example, as shown in Figure 1A, the Sin3 HDAC has been shown by yeast two-hybrid analysis to interact with mouse HCF-1 at residues 610 722 in Basic region Domain 1 (these residue numbers are the same in human and mouse HCF-1).
Protein At1g61150 is a homologue of the human Twa1 protein found in yeast by two-hybrid analysis to interact with RanBPM [ 12].
Furthermore, high throughput deep sequencing analysis and Northern hybridization validation revealed novel tRNA-derived sncRNAs that are predicted by in silico analysis to interact with endothelial functions.
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At that time, algebra and the new field of functional analysis began to interact, notably with key concepts such as spaces of p-integrable functions and Hilbert spaces.
In turn, Lef1 was in our co-expression analysis predicted to interact with Lck, known to play a key role in the TCR signal transduction pathway.
For negative controls, we used residues within PXR's ligand-binding pocket predicted by the docking analysis not to interact with BPA: Cys284, Met323, and Leu411.
DMDD will therefore also prioritise genes that, on the basis of network analysis, are predicted to interact or cooperate with genes known to cause developmental disease.
For the celiac peripheral blood dataset 91 of the 50,821 (0.179%) significantly correlated transcript-pairs that had been identified in the unconditioned co-expression analysis are known to interact.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com