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However, our kinetic analysis shows a substantial effect on kcat with little change in KM, consistent with results from a similar study with the Thr313Ile mutant of AMSH.
Neuropathologic analysis shows a substantial loss of dopaminergic neurons in the substantia nigra and accumulation of intracytoplasmic Lewy bodies, inclusions that contain α-synuclein and ubiquitin.
The analysis shows a substantial and statistically significant reduction in Fau mRNA levels in breast ductal carcinoma samples, both for patients with grade II disease (42% control value) and for patients with grade III disease (33% control value).
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This analysis showed a substantial improvement in accuracy with increasing scale.
In addition, the PCA-based motion analysis showed a substantial time-saving difference in the processing time, which was only approximately 3 min for motion analysis versus over 1 h for MODAPTS.
However, western analysis showed a substantial amount of U2AF65 in S100 extract (Figure 1E).
The results of the traffic analysis showed a substantial drop in traffic to ICV websites following the credit card and shipping bans.
WB analysis showed a substantial reduction in WRAP53 expression after siWRAP53 treatment.
In addition, the microarray analysis showed a substantial increase in STAT-3 mRNA level at 4 6 h after PHx.
This retrospective database analysis showed a substantial incremental burden of ALD among patients with HCV enrolled in a large state Medicaid program.
Immunoblot analysis showed a substantial reduction of GSK-3β or GSK-3α isoforms in these experiments (Fig. 5F, lanes 4-6, 8-10).
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