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A reasonable range for sensitivity analysis should be provided and justified.
The skills of primary level data collectors should be improved through additional schooling sessions and the few senior staff involved in statistical analysis should be provided additional training on database management.
For computational publications, an essentially still open question is whether or not executable versions or source code of in-house generated computer programs used for a particular analysis should be provided when a study is published.
[Editors' note: the author responses to the re-review follow.] Reviewer 2: 1) For Figure 4, immunohistochemical analysis should be provided for Nestin/BrdU and Tbr2/Dcx at all time-points in which BrdU was measured.
Specifically, here are the experiments suggested by the reviewers: Reviewer 2: 1) For Figure 4, immunohistochemical analysis should be provided for Nestin/BrdU and Tbr2/Dcx at all time-points in which BrdU was measured.
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To understand potential sources of bias, a non-responder analysis on baseline characteristics should be provided (Table 3, rec. 10).
2) In the determination of the koff for t1A, a test statistic or some other analysis (e.g., residuals) should be provided showing the statistical confidence that the data are better explained by a double exponential than a single exponential.
Does the evidence really support this? 2) In the determination of the k off for t1A, a test statistic or some other analysis (e.g., residuals) should be provided showing the statistical confidence that the data are better explained by a double exponential than a single exponential.
At least one input set (FASTA format file) should be provided for the analysis.
To support the analysis and management of ED operations, relevant data should be provided in an intuitive way.
The first type of information gap analysis compares the properties provided for each concept with those that should be provided according to Table 2.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com