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Using the data-adaptive sum test, collapsed analysis of the uncommon and rare variants (MAF <0.05) did not reveal any significant associations with CSS for all the rare variants (P = 0.45) or just rare exonic variants (P = 0.59).
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Using synovial biopsies from two new cases of MAA, we here present the first immunohistochemical analysis of this uncommon entity.
A recent comprehensive safety analysis confirmed the uncommon occurrence of this side effect and also pointed out the need to avoid pharmacokinetic interactions with concomitant drugs caused by shared mechanisms of metabolism by the cytochrome P450 (CYP) system in the liver [ 3].
Second, and again an issue important to the analysis of uncommon tumor types, is the question of peak detection and target identification from copy-number alteration when the analysis is based on small sample sizes (∼20 50).
This is especially important for the analysis of uncommon tumor types where source material is at a premium and the elimination of samples a distinct drawback.
According to a 2012 analysis of the Georgian population, BL is uncommon, and only 47 cases of nodular and 181 cases of diffuse non-Hodgkin lymphoma have been registered [ 6].
Analysis of other uncommon fusion genes such as TFG and KIF5B, which have been previously reported in lung cancer, were not investigated (Shinmura et al, 2008; Takeuchi et al, 2009).
Leaw et al. showed that sequence analysis of the ITS region could not identify phylogenetically related species and uncommon yeast [ 11].
In-depth analysis of the data collected suggests that it was the notion of anonymous blood donation that was uncommon and unacceptable.
Scientific analysis of the paint suggests that the portrait was done during Shakespeare's lifetime, but there is no mention on the front or back of who the subject is -- a not-uncommon occurrence at that time.
It has the following advantages: (1) it is suitable for the analysis of highly dimensional and uncommon data; (2) it can accept missing values and process noise of the information.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com