Our analysis of the previously reported 732 full-length cDNA sequences from Toxoplasma gondii [ 11] and 644 full-length cDNA sequences from Cryptosporidium parvum [ 12] revealed average sizes of 1,539 bp and 1,399 bp respectively.
However, we conducted multivariable analysis of the previously reported SNPs that were significantly associated with survival adjusting for age, stage and grade using 29,360 samples from the COGS study.
This analysis of the previously reported GEMOX and erlotinib trial for BTC demonstrated that ETS 6 weeks after first-line GEMOX treatment either with or without erlotinib correlates with PFS and OS.
For the analysis of sibutramine, the previously reported adverse effects including hypertension, myocardial infarction, heart disease, anorexia nervosa and bipolar disorder [14 17] were also successfully identified by ChemDIS.
However, our analysis and all of the previously reported off-target analyses in mice provide limited genomic context, and the potential risk of off-target mutagenesis in disparate parts of the genome is undeniable.
This analysis expands the previously reported number of members in C. elegans miRNA families [43], [51], [63], [64] and establishes 1 new sequence-related group containing miRNAs cel-miR-78 and cel-miR-272.
This analysis confirmed the previously reported specific expression of MtGS2b in the seeds [ 20] and quantified the differential expression of MtGS1a, MtGS1b and MtGS2a in defined organs of the plant.
Additionally, BLASTn analysis indicated that none of the previously reported microsatellites were within these 16 supercontigs, but that two of them are located in other supercontigs with known genetic marker loci (CxpGT4, gb-AY423738, supercontig 3.5, chromosome 2-36.1 2-36.1i4, gb-AY958079, superCxqTri43.208, chromosome 3-26.3) [24].
Using cell cycle analysis, we screened many of the previously reported CBD targets, and identified the involvement of a mitochondrial target.
In addition, this analysis revealed that the previously reported suppression of sae2∆-mediated DNA damage hypersensitivity by Ku loss (Mimitou & Symington, 2010; Foster et al, 2011) was considerably less effective than that caused by mre11-H37R or mre11-H37Y mre11-H37Y
Association analysis of the individual SNPs, and of the previously reported three-SNP haplotype in the VEGF promoter was performed using UNPHASED version 3.0.9 [22].
