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Analysis of the endpoints will be based on the difference between baseline measurements and measurements at the end of the intervention period with group allocation as independent variable.
All SCr values used for analysis of the endpoints are measured at the central clinical laboratory.
Kaplan-Meier (Mantel-Cox log rank) analysis of the endpoints; *Mean value.
The current article is limited to the analysis of the endpoints until 6 months.
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Additionally, an analysis of the endpoint "alive and without ventilator ≥20 days within the first month" was performed.
In this latter circumstance, there may be only one endpoint of interest in the clinical trial, but several competing endpoint analyses are available (e.g., an analysis of the endpoint that is adjusted for clinical center versus an analysis that is adjusted for geographic region versus an unadjusted analysis).
Univariate analysis of the endpoint: cardiovascular mortality (not shown in Table 2) resulted in the same significant predictive factors, but with higher HRs.
Analysis of the endpoint supernatants by SDS PAGE reveals that incubation of Aβ1 42 with trypsin-α2M results in proteolysis of the peptide (Fig. 2d, lane 3).
SDS PAGE analysis of the endpoint supernatants reveals that no detectable I59T lysozyme remains in solution when incubated alone, whereas in the presence of native α2M, a large majority (>90%) of lysozyme remains soluble (Fig. 1d).
Significantly, analysis of the endpoint supernatants reveals that soluble, full-length Aβ1 42 is present in the (i trypsin-α2M sample and no degradati trypsin-α2M are obsample (Fig. 2d, land 4).
Analysis of the endpoint fermentation broth was performed using HPLC measuring soluble sugars (glucose, cellobiose, arabinose, and xylose) and the primary fermentation metabolites for C. thermocellum (acetic acid, lactic acid, ethanol, and formic acid).
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