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Therefore, the detailed analysis of the coil to CSS connections, the so-called central support elements (CSE), is a critical item.
An uncertainty analysis of the coil position measurement is conducted based on geometry and refractive index which can be readily applied to measurements obtained using this method.
The present article describes the implementation of a birdcage coil simulator, operating in high-pass and low-pass modes, using magnetostatic analysis of the coil.
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Sequence level changes are examined through the analysis of the coiled coil, which is a crucial domain facilitating self-assembly and interaction with other proteins.
Fault analysis of the coils indicated that ITER ELM coils are robust and show good characteristics even with 11% of dead coils.
Analysis of the coiled-coil domain was performed with the following programs: COILS (http://www.ch.embnet.org/software/COILS_form.html) [52], Paircoil2 [53] and MultiCoil [77].
The coiled-coil domains of each protein were identified using the 28-residue window output from the COILS program (http://www.ch.embnet.org/software/COILS_form.html) and to maintain consistency with our previous study, only those regions of the sequence where the score was ≥0.5 were used for the analysis of the coils [21], [48].
Unfortunately, an earlier functional analysis of coiled coil regions of BicD did not test the importance of this particular coiled coil domain and only included one of the phosphoserines, S186 [35].
Our analysis finds that the coiled coil domains of insect silk proteins have several common structural anomalies including a high prevalence of alanine residues in core positions.
Significantly, sequence and phylogenetic analysis of coiled coil proteins (Fig. 1) clearly shows that RHAMM does not contain a TACC domain and instead forms a distinct family of proteins in the coiled coil superfamily, and is not a direct descendant of the ancestral TACC gene.
Analysis of the structure with the coiled-coil software SOCKET (Walshaw and Woolfson, 2001) identified 84 'knobs into holes' interactions; all are of type 4 with packing angles of between 45 and 60° as commonly observed in trimers.
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