Sentence examples for analysis of sequence and structure from inspiring English sources

These three methods complement one another, together making possible a comprehensive analysis of sequence and structure variations of the human genome.

Analysis of sequence and structure databases addresses a fundamental safety question: does the introduced protein share any sequence or structural similarity with proteins known to pose possible toxicological hazards?

The database-driven analysis of sequence and structure-based signatures of kinase SNPs has clarified salient aspects of sequence conservation patterns and structural profiles of cancer-causing mutations, including the emergence of structurally conserved tumorigenic hotspots across multiple protein kinases.

Kinome-wide analysis of sequence and structure-based signatures of cancer mutations, revealed that a significant number of cancer mutations could fall at structurally equivalent positions within the catalytic core.

Several services are available to identify the effect of nsSNVs on individual protein function which is done mainly through sequence conservation analysis and/or through mapping of sequence and structure features to individual proteins [8 10].

We have set out to identify such genes and analyze their likely functions using a combination of sequence and structure analysis tools.

The combined analysis of its sequence and structure reveals a structural fold originally associated with periplasmic binding proteins.

Analysis of the sequence and structure of the BH3 binding grooves showed that, despite low sequence identity, M11 has structural similarities to Bcl-xL, Bcl-2, and Bcl-w.

The analysis of the sequence and structure of HisA and HisF depicts a likely scenario for divergent evolution of (at least) some of the proteins belonging to the TIM-barrel faminterestinglyingly HisA is the only one maintaining an almost perfect subdivision in two modules half the size of the entire gene and sharing a high degree of sequence similarity.

The integration and mapping of diverse data types in CKMD provided a convenient framework for kinome-wide analysis of sequence-based and structure-based signatures of cancer mutations.

In this work, using a combination of comparative genomic analysis, sequence and structure comparisons, the authors reveal that PafA is a distant evolutionary relative of the gamma-glutamyl-cysteine synthetase/glutamine synthetases.