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SonoVue® is approved for ultrasound examination to improve echogenicity of blood and vessel structures from time-intensity curves obtained during constant infusion, and using dedicated software for the analysis of replenishment kinetics.
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Thus, the new phantom allows standardized analysis of contrast replenishment kinetics using real-time perfusion imaging techniques at flow velocities comparable to those of the microcirculation.
Analysis of the replenishment kinetics was performed using the mathematical model f(t) = A(1 − e−βt), with A representing the blood volume and β the microbubble velocity.
Analysis of the replenishment parameters revealed a strong linear relationship between parameter β and flow (r = 0.994) as well as A∗β and flow (r = 0.984) in the observed flow range.
Post processing analysis of the destruction-replenishment video clips, recorded as DICOM files, was performed using a prototype software (Bracco Suisse SA, Switzerland).
To analyze the impact of replenishment and inventory costs, we conducted an "a posteriori" analysis.
These outcomes were further endorsed by mtDNA depletion and in vivo replenishment during tumorigenesis and analysis of patient tumor samples, which support the hypothesis that mtDNA variants in complex I act as initiators of GBM.
Japan's population doesn't have that source of replenishment.
We saw a significant amount of replenishment was missing".
If you extract resources at a rate beyond the level of replenishment, your stock will collapse.
There are reserves of trust, in a perpetual state of replenishment or depletion.
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