Sentence examples for analysis of occluded genes from inspiring English sources

Here, we describe chromatin analysis of occluded genes.

We uncovered evidence that DNA methylation plays a causal role in maintaining occlusion for a subset of occluded genes.

We found that DNA methylation plays a causal role in maintaining occlusion for a subset of occluded genes.

The identification of occluded genes by our assay provides a hitherto unavailable functional readout of chromatin state that is distinct from and complementary to gene expression status.

A key test of this model is the identification of biallelically occluded genes.

Here, we describe the trans complementation assay, which allows the systematic identification of biallelically occluded genes.

We then examined the resulting expression patterns of the 24 occluded genes under these culture conditions.

We then performed extensive bisulfite sequencing to analyze methylation patterns of a subset of 10 genes, five of which were chosen from the 24 occluded genes, whereas the other five were selected from the 10 transactivated genes.

Using trans complementation, we uncovered occluded genes in a variety of mammalian cell types (2).

Importantly, occluded genes remained silent regardless of post-fusion incubation time (Supplementary Material, Fig. S2), demonstrating the temporal stability of the occluded state in fused cells.

Our recent study identified occluded genes in a number of cell types (2), including the human lung fibroblasts MRC-5 (hereafter denoted hLF).