Sentence examples for analysis of linkage from inspiring English sources

For the analysis of linkage disequilibrium (LD) patterns and selection of tagging SNPs we used Haploview software [57].

The modification used by MSP allows for the analysis of linkage regions by accounting (correcting) for the effects of crossover, marker spacing, family structure and original linkage methods used.

Chromosomal position of the CNR1 gene was obtained from the UCSC human genome browser (http://genome.cse.ucsc.edu/cgi-bin/hgGateway). SNPs within the region of interest were downloaded from the International Human Haplotype Map for the Centre d'Etude du Polymorphisms Humain (CEPH) and entered into Haploview for an analysis of linkage disequilibrium (LD) and tag SNP assignment.

Here, to investigate the potential for allelic association studies in Thailand, an analysis of linkage disequilibrium was first undertaken with a sample of 100 P. falciparum clinical isolates, using one set of microsatellite loci widely distributed in the genome, and another set clustered within a ∼140 kb region of one chromosome.

Analysis of linkage equilibrium (LE) between alleles at all pairwise combinations of loci showed that only 8/21 combinations are in linkage equilibrium when all isolates are treated as a single population, but in the sub populations the number in LE doubled (W, 16/21; X, 18/21; Y, 15/21; Z, 16/21; Table S6).

The variance-components model is advantageous in detecting QTL in the following two aspects: first, it combines the analysis of linkage and association and would increase the power of detecting QTL when the marker, itself is not the QTL, is associated with the QTL.

The Chapter on Brazil and Costa Rica (Chapter 5) provides an interesting comparative analysis of linkages between agricultural expansion and the policies adopted in the two countries.

In-depth understanding of these alterations, and comprehensive analysis of linkages between them may shed light on revealing the molecular mechanisms underlying NSC/NPCs aging.

Key sector analysis of linkages in the economy began in the late 1950s, with seminal contributions by Nørregaard Rasmussen [16], Chenery and Watanabe [3], Hirschman [7], Augustinovics [1], Laumas [9 11], and Lenzen [12], among others.

Further research is needed to find out why this was the case, including in-depth analysis of linkages between food insecurity in this area of Uganda and extremes in climatic seasons as well as household parameters including gender, ethnicity, being a migrant and livelihood diversification.

Below we present the findings according to each health system component, followed by an analysis of linkages between elements.