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Similarly, we are limited in our analysis of cognitive function both because: (a) only a subset of subjects have cognitive outcome (n = 318, 44% of the cohort), and (b) although SDMT has become increasingly adopted as a measure of cognition in MS patients, it does not evaluate all cognitive domains and might thus underestimate the extent of cognitive dysfunction.
Analysis of cognitive function showed an overall benefit on cognitive measures (five trials, 3317 participants, standardised mean difference 0.08, 0.01 to 0.15, P=0.02) for patients who underwent comprehensive geriatric assessment.
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The meta-analysis of cognitive function in children with type 1 diabetes by Gaudieri et al. (15) found mildly lower cognitive scores relative to HC participants across various domains, particularly in those children with early onset as defined by diagnosis before age 7.
To fill this gap, the current study provides a systematic review and meta-analysis of cognitive functioning in adults receiving HCT.
In a recent study involving 148 participants treated with haemodialysis or peritoneal dialysis, cognitive impairment (particularly executive function) was independently correlated with functional dependence in activities of daily living, although numbers of affected participants in this study was small and a comprehensive analysis of domains of cognitive function was limited.
The non-surgical control sample served to provide reference data for the surgical group for longitudinal and cross-sectional analyses, but were not included in analyses specifically pertaining to post-surgical outcome, including analysis of brain correlates of cognitive function and in regression analysis of clinical predictors of post-surgical outcome.
Evidence from prospective studies, reviews, and a meta-analysis support distinctly different trajectories of cognitive function in schizophrenia and bipolar disorder over the emerging course of illness onset (Lewandowski et al. 2011; Trotta et al. 2015).
Ko et al. [ 11] used latent profile analysis to extract groups on measures of cognitive function, social support and personality in the Health and Aging Study.
A second analysis comparing the 5-year assessments of cognitive function with those collected about 1 year later showed a significant improvement in cognitive function following completion of endocrine therapy for both treatment regimens; the magnitude of improvement was not significantly different between treatments [ 32].
Group comparisons of cognitive function were performed using analysis of covariance (ANCOVA) controlling for gender.
Recovery of cognitive function after traumatic brain injury: a multilevel modeling analysis of Canadian outcomes.
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