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Immunoblotting and mass spectrometry analysis of CIA joint tissue lysates identified citrullinated tropomyosin 1 alpha, actin, calgranulin-B and ATP synthase beta chain (Table 1).
In mice, analysis of CIA gene expression profiles revealed a seven-fold increase in FAP, DPP IV, and MMP gene expression in inflamed paws as compared with non-inflamed paws [ 29, 30].
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Although IgG2a and IgG2b anti-CII antibodies were also detected in CIA mice, treatment with JWH133 did not significantly alter the levels of antibodies (data not shown).
Rob Newman is on stage at London's Tricycle Theatre in the middle of a detailed analysis of the 1953 CIA-backed Iranian coup.
To compare values among the control, CIA-arthritic, and CIA-resistant groups, one-way analysis of variance (ANOVA) was performed, followed by Student-Newman-Keuls multiple comparisons test when differences were detected.
(Note the singularity of "CIA", and its lack of a definite article).
It is the second kind of cia examples which connect our topic to fractal sets.
Our results further indicated that navelbine affected the incidence of CIA less than docetaxel, but no significant differences were found.
To determine if FlpA is required for the delivery of Cia proteins to host cells, we performed protein delivery assays.
Quantitative analysis of Msi1 expression in the different groups revealed significantly higher expression in joints with CIA-induced articular lesions than in joints without lesions (P < 0.0001, Student's t-test, Figure 4).
Detailed analysis of synovial tissues showed that the number of proliferating-cell nuclear antigen (PCNA -positive cells in CIA-syno+/- mice was not different from that in syno+/+ mice, but TdT-mediated dUTPCNA -positiveelling (TUNEL) analysis demonstrated a significellsincrement of apoptotic cells in CIA-syno+/- mice.
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