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Another challenging problem associated with the use of NMR techniques in metabolome analysis is low sensitivity, but some possibilities for resolving these shortcomings have been proposed [64], [65].
The diagnostic yield of stool analysis is low in patients with higher CD4 cell counts.
A third issue for association analysis is low power for rare variants that medical sequencing is expected to uncover.
However, the power of this analysis is low (0.26), as the non-responder group consisted of four children only.
Though the power of the statistical analysis is low, the large variation in the mating frequency among individual males suggests that morphs do not differ strongly in this respect.
It should be pointed out that the sensitivity of the FACS analysis is low with regards to the MHC class II+CD11b+ cells and CD4+ T cells found in the immunohistochemistry. Therefore, FACS analysis will not reveal sequential steps.
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The next most important feature in their analysis is low-frequency edges.
Since current manual FISH signal analysis is low-efficient and inconsistent, which limits its clinical utility, developing automated FISH image scanning systems and computer-aided detection (CAD) schemes has been attracting research interests.
As a result, the methodological quality of the six trials that have been included into our analysis was low.
Independent prognostic markers in multivariate analysis were: low serum albumin (HR = 11.1), poor performance status (HR = 3.8), ≥5 CTC/7.5 ml (HR = 3.8) and triple negative subtype (HER2+ and hormone positive vs triple negative: both HR = 0.2).
The interest rates used in this analysis are low enough to make the impact of these choices rather small in the final results.
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