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In a process transparent to the user, the gene model corresponding to the reference sequence defined for the analysis is downloaded automatically from Ensembl.
The taxonomic tree used in our analysis is downloaded from the NCBI taxonomy database, however our analysis can be redone with a different taxonomic tree.
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Datasets of A. thaliana RNA-Seq reads for de novo contig assembly and comparative analysis were downloaded via the SRA download page (http://www.ncbi.nlm.nih.gov/sra).nih.gov/sra
Gene groups for the perturbation score analysis were downloaded from http://www.SABiosciences.com.
Predicted operons for the analysis were downloaded from the BioCyc R. palustris database [37].
Previously described sequences of known viruses included in the phylogenetic analysis were downloaded from the NCBI and the GOS databases.
The other 11 genomes included in this analysis were downloaded from NCBI, thus constituting a total of 15 strains in the comparative analysis (Table 2).
*Data for this analysis were downloaded on June 6 , 2013
DNA sequences of bacteria for analysis were downloaded from multiple databases, such as NCBI (the National Center for Biotechnology Information).
Lastly, the GO data for various GO term analysis were downloaded from http://www.geneontology.org.org
The annotations file used for this analysis was downloaded from NCBI (NC_000964.ptt).
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