Following QTLMAP analysis, estimates for five significant genome-wide and four suggestive QTLs are summarized in Table 3.
The pooled, random effects meta-analysis estimate for the proportion of patients who experience one or more episodes of FN on docetaxel is 5.95% (95% CI 4.22 8.31).
The pooled, random effects meta-analysis estimate for the proportion of patients who experience one or more episodes of FN on docetaxel was 5.95% (95% CI 4.22 8.31) based on 13 studies, comprising 1609 patients.
The best evidence synthesis of studies that fell into the high tertile of the quality score yielded a meta-analysis estimate for the relation of physical activity to renal cancer of 0.78 (95% CI=0.66 0.92; t=0.02).
The fixed effect meta-analysis estimate for these 22 unpublished studies (0.15, 95% confidence interval 0.08 to 0.22) was far lower than the one for published studies (0.41, 0.37 to 0.45; fig 2B), adding further support that serious publication biases are present in the journal data.
In analyses limited to the 18 studies where results for adenomatous polyps were separated from all polyps (i.e., hyperplastic, malignant polyps), the meta-analysis estimate for the association between physical activity and risk of polyps was largely unchanged (RR=0.83, 95% CI: 0.73 0.93).
(XLS 27 kb) Additional file 13: Sensitivity analysis of comparing meta-analysis estimates for pre-post vs. pre-follow-up measurements.
Meta-analysis estimates for common and novel bi-allelic SNPs in South Asians were compared with white Europeans from the DIAbetes Genetics Replication And Meta-analysis (DIAGRAM) consortium.
Our review also considers a range of other cancers, and Table 1 also presents meta-analysis estimates for stomach, bladder and overall cancer.
dCovariance analysis estimate with 95% confidence interval for difference.
cCovariance analysis estimate with 95% confidence interval for difference.
