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Between 1 January 2008 and 25 October 2010 (analysis cut off) we relied upon patient-reported malignancies that were subsequently verified by the treating doctor and/or histology reports.
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Every one of Miliband's six questions was what is known in higher political analysis as cut off at the knees.
All the data in this analysis were cut off at the end of follow-up on November 12 , 2011
Using ROC analysis, cut-off values of miR-126 were determined to discriminate asbestos-exposed subjects from controls (ΔCT = −3.5; sensitivity 60% and specificity 74%) and from MPM patients (ΔCT = −4.5; sensitivity 73% and specificity 74%).
Multiple logistic regression (using automated backward variable selection) was performed including those clinical parameters that showed at least a trend towards significance in univariate analysis (cut-off p-value = 0.1) using SPSS 15.0.
Prior to analysis, images were slice time corrected, reoriented to correct for subject motion, spatially normalised to the standard Montreal Neurological Institute template, smoothed with an 8 mm full-width at half-maximum Gaussian kernel, and high-pass filtered prior to analysis (cut-off period 180 s).
The univariate analysis cut-off for inclusion in the logistic regression analysis was p < 0.20.
The final data analysis cut-off date was November 30, 2011.
For the rest of the analysis, cut-off criteria 'A' was used as the definition of disability.
The continuous variable 'platelets' in model 2 was dichotomized after scatterplot analysis (cut-off value for platelets at 50.000/mm3).
Person-years for biologic-naïve patients were calculated from the date of enrolment in ARAD until death or analysis cut-off date (25 October 2010).
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