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Additionally, in a larger intervention study, a process analysis could be undertaken to identify how the intervention might have worked.
Alternatively, a cost-benefit analysis could be undertaken from the perspective of persons with disabilities, taxpayers and society as a whole.
Undoubtedly further sensitivity analysis could be undertaken, but the model still cannot efficiently reflect the interactions among these uncertainties because each solution can only provide a single result corresponding to variations of the uncertain inputs.
Further analysis could be undertaken in time; however, unless changes are made in relation to regulatory requirements or orthodontic companies make a decision to embrace independent clinical research at an earlier stage, it is likely that the status quo will continue to apply.
Moreover, the EQ-5D instrument was used to enable the calculation of QALYs so that a cost-effectiveness analysis could be undertaken.
Citations were checked to see that they were of methodologically sound research, and could be validly generalised to the particular telehealth setting, to determine whether a cost-minimisation analysis could be undertaken.
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This was a pilot study hence the sample size is small and this has restricted the degree of analysis that could be undertaken.
The only analysis that could be undertaken was to examine a difference between groups regarding function at 2 and 5 years, which again demonstrated no difference.
Understanding the substrates and catalytic products for enzymes will help to predict whether interactions are possible, and if needed, targeted compositional analysis of metabolites could be undertaken if interactions between enzymes are suspected.
Differentiating between these competing hypotheses could be undertaken with an analysis of when strategic over-ocean flocking (or more generally, roosting behavior) ought to occur.
The array allows screening of far more ligands than could be undertaken in a structural analysis.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com