This suite of analyses illustrates the importance of careful consideration of geographic areas of analysis and extents of applicability in niche modeling exercises.
In the multifactorial analysis, presence and extent of peritumoral edema in primary glioblastoma was associated only with depth of tumor or the extent of necrosis, implying that edema is the result of severe hypoxia.
Motivated by prior findings that severity of coronary artery disease as assessed during cardiac catheterisation may affect the use of reperfusion therapy differently in women and men, 25 we conducted an interaction analysis between sex and extent of coronary disease.
In the univariate Cox regression analysis, sex, age and extent of surgery were not found to be statistically significant predictors for OS or PFS, whereas PS was found to influence both OS and PFS (Hazard ratio[HR] = 2.27, 95% CI 1.33-3.86; Wald's p = 0.003 and HR = 2.45, 95% CI 1.46-4.13; Wald's p = 0.001, respectively).
On multivariate analysis (age, KPS and extent of surgical excision), PSA-NCAM expression was the unique predictive parameter of OS [hazard ratio (HR): 2.01 for patients suffering from a GBM with PSA-NCAM content >10 pg/μg of protein (CI 1.01-4); p = 0.046, n = 56] and DFS [HR: 2.89 for patients suffering from a GBM with PSA-NCAM content >10 pg/μg of protein (CI 1.34-6.27); p = 0.007, n = 54].
To allow a consistent intercomparison of results across research groups, participants were requested to submit results in a standardized format and with a list of items describing the details of source apportionment analysis (e.g., type and extent of rotation, treatment of outliers, criteria used to include species in the analysis).
The fracture analysis of impact samples and extent of fillers dispersion were visualized by SEM.
Particular attention was given to the analysis of the type and extent of landscape activities and their relationship with farm characteristics.
Of the 12 compounds, six were selected for further analysis and the type and extent of inhibition determined.
Analysis of the degree and extent of multiple bone metastases, cumulatively called as the extent of disease (EOD), has been based on visual diagnosis of whole-body images (Imai et al., 1992).
