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Retrospective analyses would be needed to confirm this hypothesis.
To resolve this issue further dating analyses would be needed.
Considering the possible universality of SNVCs, those finer analyses would be needed in a full search for disease-causal alleles.
Further analyses would be needed to determine which genes were targets of positive selection in these regions.
Further analyses would be needed to assess the predictive validity of these measures for patients in treatment for longer periods.
Moreover, there are rarely only two interventions under consideration in clinical practice, and a plethora of analyses would be needed to draw conclusions.
Similar(48)
While DCM formulation allows such analyses, more (precise) data would be needed to disambiguate between alternative models of anticipatory bursting.
This raises the question of whether S. magdalenae may be the same species as S. contortum and thereby represent yet a further example of the wide range of this species; molecular analyses on S. magdalenae would be needed to clarify this.
Further analyses of their kinase potential would be needed to conclude.
To truly discriminate between the two hypotheses, analyses tending to eliminate potential LBA, such as the use of sequence evolution models that accommodate better differences in evolutionary rates (e.g. CAT), the progressive elimination of fast-evolving sites from their analyses or amino acid recoding would be needed.
Thus we are rejecting the paper on the grounds that the main new analyses are not as compelling as would be needed for eLife.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com