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Data for these analyses were extracted from patient records in the UK General Practice Research Database (GPRD) from January 1997 to the end of June 2007, a period when all inhaler types under study were available.
Multiple subset alignments, to be used in comparative analyses, were extracted from the master alignments based on their metadata values, using the Antigenic Variability Analyzer (AVANA, http://avana.sourceforge.net), developed by the authors to support information-theoretical analysis tasks [17], [18].
Data used for these analyses were extracted from the eligible studies included in this review.
Second, DNA samples used for methylation analyses were extracted from peripheral blood cells.
Data for regression analyses were extracted from these layers using ArcTools at 3-PSA level.
Sites suitable for further phylogenetic analyses were extracted from the alignments with Gblocks 0.91b assuming less stringent criteria (Castresana 2000).
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RNA for microarray analyses was extracted from three independent replicate cultures of U937T_pUHD10S cells using the RNeasy Plus mini kit (Qiagen) according to the manufacturer's instructions.
DNA for genetic analyses was extracted from the suspensions and pure cultures as described previously (6, 8 ).
Data for present analyses was extracted from Estonian HIV database on 2nd of January 2014 and it comprised subjects diagnosed HIV-positive from 2000.
Data analysed were extracted from the databases of PBCRs located in major Brazilian cities as described previously [ 10].
The cells being analysed were extracted from the whole image and single Z sections analysed using the colocalization tool in the Zeiss Zen software.
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