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Urine samples for both pharmacokinetic and pharmacodynamic analyses were collected for 24 h before administration and for 0 2, 2 4, 4 6, 6 8, 8 10, 10 12, 12 14, 14 16, 16 24, and 24 48 h after administration for all groups, and for the additional time periods of 48 72 and 72 96 h for the 15 and 25 mg groups.
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Blood samples for genetic analyses were collected from all individuals.
Baseline data for our analyses were collected from 1979 to 1997.
Blood samples for immunological analyses were collected from all patients upon enrollment and after a one-year interval.
All exposures in our analyses were collected at baseline for all participants.
Blood samples for pharmacokinetic analyses were collected, and safety and tolerability were assessed.
Samples for RNA analyses were collected by filtration during fermentation after consumption of 15 g/L sugars.
Samples for transcriptome analyses were collected at all time points.
Samples for laboratory analyses were collected before dosing.
Data for the analyses were collected on the implementation of 'Safe Community' programmes in Swedish municipalities.
In addition, risk factors for both analyses were collected by self-report, which may have been inaccurate.
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