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Differences between groups at specific time points or for post-mortem tissue weight analyses were assessed with single factor ANOVA followed by pairwise comparisons using Tukey's HSD test.
Other statistical analyses were assessed with the Mann-Whitney U test.
Bivariate analyses were assessed with χ tests and Student t tests.
Means were compared with T-test and the correlation analyses were assessed with the Pearson/Spearman correlation coefficient.
All analyses were assessed with robust variance estimates to adjust for clustering of patients in general practices.
Statistical analyses were assessed with SPSS for Windows v12.0.1 (SPSS Inc., Chicago, IL, USA) and SISA (http://home.clara.net/sisa/).clara.net/sisa/
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The potential effect of recombination on the phylogenetic analyses was assessed with the GARD method [ 27].
Agreement between intermittent and continuous blood gas analyses was assessed with a Bland-Altman plot [ 10] obtaining: bias (mean difference between methods), precision (± 2 SD of bias) and limits of agreement.
Convergence and mixing of chains in the Bayesian phylogenetic analyses were assessed by examining output files with the AWTY (Are We There Yet) graphical exploration software [ 36].
Immunohistochemical analyses of these lymphangiomas were assessed with Lyve-1 and CD45 antibodies to label lymphatic vessels and inflammatory cells, respectively.
Differences between conditions were assessed with analyses of variance (ANOVA).
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