Sentence examples for analyses of this variant from inspiring English sources

Detailed biochemical analyses of this variant revealed possible causes of the in vitro/ in vivo disparity of function, and reinforced the concern that standard in vitro enzymatic assays, as performed in many clinical laboratories, may be insufficient to predict fully the in vivo function of some variant alleles.

Replication analyses of this variant in 1,142 Caucasian patients with eating disorders from five European countries confirmed the association of this variant with all eating disorder subtypes including AN, AN-restricting type, AN-binge-eating/purging type and BN [ 53].

However, analyses of the variant with SIFT, PolyPhen, and SNPs&GO showed that most likely the change is not pathogenic.

The results of the functional analyses of the variants investigated in this study are summarised in Table 2.

Significantly, the analyses of these variants revealed that NDR1-PIF, an NDR1 variant containing the PRK2 hydrophobic motif, remains hyperactive independent of hMOB1/NDR1-PIF complex formation.

We first performed single-locus analyses of the variants that surviving Hardy-Weinberg equilibrium test (n = 106).

This indicates that, as reported previously [35], [76] [78], at least in some cases it might be feasible to define tag-SNPs as proxies for CNV alleles in certain populations that could be helpful in future analyses of those variants (Table S8).

Further analyses of these variants by genotype did not strengthen the association.

At this stage, because we only have samples from the index individuals, no segregation analyses of the variants have been performed, but these families clearly warrant additional studies.

However, further analyses have documented an association of this variant with mild hearing loss in 9 of 10 genotypic combinations (30), in accord with other studies of the allele (31– 31).

Largest head-to-head comparative two-dimensional strain analyses of variant forms of left ventricular hypertrophy.