Sentence examples for analyses of the mutations from inspiring English sources

Analyses of the mutations that enhance fitness at 37°C may shed light on the physiological basis of this trade-off.

Furthermore, PIK3CA mutations were always found in esophageal cancer [ 23, 24] and further functional analyses of the mutations are warranted to determine whether or not they may be potentially useful targets of therapy for esophageal cancer [ 25].

Logistic regression and other statistical analyses of the mutation accumulation data were performed in R (www.r-project.org/).org/

Analyses of the mutation spectrum using a polymerase chain reaction-based deletion screening and DNA sequencing procedure showed that a high proportion of HPRT- and GPT- mutants induced by X-rays carry deletion mutations.

Sequencing analyses of the mutation hot spots of TP53 have demonstrated that hemizygous mutations (i.e. mutation and LOH) were detected in the mucosal samples of 1 of the 3 intramucosal cancers and 1 submucosal cancer with a TP53- pattern, as well as the invasive parts of the 4 advanced cancers that were informative for TP53 mutation analysis.

The association analyses of these mutations with litter traits were carried out in Large White and Chinese DIV line pigs.

Biochemical analyses of these mutations have focused on the kinase activity of LRRK2.

Exploratory analyses of the other mutations were conducted to understand the full spectrum of change during treatment: There was no statistically significant increase in any of the other 8 possible mutation types, including all transversions, and, the overall p-value for any effect of treatment on transversion mutations, corrected for multiple testing, was 0.38.

To investigate the role of ASXL1 mutation in disease progression, sequential analyses of the gene mutation were performed in 305 samples from 112 patients, including 32 patients with ASXL1 mutation at diagnosis and 80 patients without the mutation.

Further analyses on the origin of the mutations showed mutational mosaicism in one unilaterally affected father of a bilateral proband and incomplete penetrance in two mothers.

These findings suggest that it is not only the presence or absence of a mutation that should be considered in analyses of the impact of mutations on clinical outcome, but also the size of the subpopulation a mutation affects.