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Functional and molecular analyses of the altered genes revealed novel pathways, such as hepatocyte nuclear factor 4α, potentially regulating the pollutant responses.
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Results of KEGG pathway enrichment analyses of the significantly altered proteins quantified in the ethanol-producing strain (a) and the lactic acid-producing strain (b).
In-depth analyses of the genes altered by PML knockdown showed that PML knockdown interferes with a molecular network of genes involved in the cell adhesion, cytoskeleton, and signaling transduction by extracellular cytokines/chemokines (Additional file 3: Figure S2).
Most of the altered eggs will die.
Furthermore, the reduced number of patients presenting with ARDS limited, and may have biased, the evaluation of the diagnostic capability of capillary analyses of highly altered gasometrical values.
We thank M. Fuangthong and S. Soonsanga for their initial analyses of functionally altered perR variants, E. Madsen for help with the anaerobic experiments, S. Zhang and R. Sherwood for assistance with mass spectrometry, and G. Storz, P. Kiley, J. Imlay, and C. M. Moore for comments.
To identify biological functions common to SAC3 and MED31, we performed gene ontology (GO) analyses of significantly altered mRNAs.
The predictions of the mechanistic model were confirmed by analyses of mutant plants altered in initiation or emergence.
Statistical analyses of altered SC and FC were carried out on the basis of structural and functional group matrices, containing the means of corresponding nonzero entries in individual matrices of all members of the group, i.e. patients or healthy controls.
These considered both contributions from prolonged INa,L, reported in earlier analyses of Scn5a+/ΔKPQ (20), and altered maximum INa,T.
Analyses of the three large transcriptionally altered diabetic datasets (Mexican_Hs, IR_Hs and DN_Hs) demonstrate that the oxidative stress induced deregulation of β-catenin plays an important role in causing kidney diabetic complications by the down-regulation of CDH5.
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