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Cross-methodologic analyses of array data should not be performed uncritically.
Thus, this preliminary study provides validation for our approach to the statistical analyses of array data.
Further analyses of array data showed that treatment with AZA resulted in demethylation (DB≤−0.2) of 6% (852 of 13,911) of the CGs methylated in control cells (Figure 2A).
All analyses of array data were performed at the University of Manchester.
SAB and DP coordinated and performed all the bioinformatic and statistical analyses of array data.
It emphasizes good experimental execution and discarding unsatisfactory microarrays rather than salvaging data through complex statistical analyses of array data of variable quality.
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Statistical and gene annotation enrichment analyses of tag profiles identified more differentially expressed genes of potential adaptive significance than previous analyses of array-based expression profiles.
To identify genes that discriminate between BRCA1- and BRCA2-associated tumors, supervised univariate analyses of array-based log2 gene expression were performed for each clone treating the modified Student t-test as the primary analysis [ 19] using the SAM procedure implemented in open source software, version 2.1.0 (http://www.r-project.org/).org/
Analyses of arrays where a catalyst was printed at variable spot concentrations confirm that the IR complex of the circuit can function as a reliable reporter of the levels of immobilized catalyst.
EM Extracted RNA for oligonucleotide arrays, performed oligonucleotide array experiments and analyses of oligonucleotide array data and contributed to drafting the manuscript.
As transcription factors and their target genes are often co-regulated, we performed meta-analyses of array-based expression data to identify regulators whose mRNA profiles are highly correlated with those of a core set of lysosomal genes.
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